From a conflicted and unhappy childhood, Parker rose to acclaim, both for her literary output in such venues as The New Yorker and as a founding member of the Algonquin Round Table. Following the breakup of the circle, Parker traveled to Hollywood to pursue screenwriting. Her successes there, including two Academy Award nominations, were curtailed as her involvement in left-wing politics led to a place on the infamous Hollywood blacklist.
Parker went through three marriages (two to the same man) and survived several suicide attempts, but grew increasingly dependent on alcohol. Dismissive of her own talents, she deplored her reputation as a "wisecracker". Nevertheless, her literary output and her sparkling wit have endured.